2022 Week Six NFL Best Bets: Buffalo Bills at Kansas City Chiefs

2022 Week Six NFL Best Bets: Buffalo Bills at Kansas City Chiefs
Image ©Jamie Germano / USA TODAY NETWORK
Frank Weber
Author:
Frank Weber
Updated: 
October 14th 2022 - 10:20 AM

Week six is packed to the gills with good games–we’ve got the Cowboys traveling into Philly to take on the red-hot Eagles, the Ravens coming into New York to see just how real the Giants are, and, of course, the rematch of last year’s Divisional round classic between the Buffalo Bills and the Kansas City Chiefs. Wow, what a slate of games.

You can be sure to find different bets for any of this week’s NFL action here at OddsSeeker. However, marquee games like this only pop up a few times a season, so a game this big deserves its own story. I’ll be giving out my four best bets for this Sunday’s game, which starts at 4:25 EST. The odds I will be using are provided by DraftKings Sportsbook. If DraftKings isn’t available in your area, don’t worry–you can check out this list of other online sports betting apps. 

Best Bet #1: Josh Allen OVER 344.5 Combined Passing and Rushing Yards (-115)

If you recall the last time these two teams matched up, then you probably remember Josh Allen passing–and rushing–all over this Kansas City defense. I suspect him to do the same here in week six, especially against this weak Kansas City defense. The Chiefs have given up an average of 277.40 yards per game to opposing quarterbacks through the air, and have only managed to come up with one interception all year. Two of the five QBs the Chiefs have faced have gone for over 300 yards: Herbert in week two (334 yards) and Brady in week four (385 yards). Seeing as how Allen has already surpassed the 344-yard mark twice this season in passing yards alone, this number shouldn’t be too hard to hit. 

Best Bet #2: Travis Kelce UNDER 78.5 Receiving Yards (-115)

Kelce is coming off a monster week where he scored FOUR touchdowns on seven receptions. However, slide your eyes down that stat line a little bit more and you’ll quickly realize–he only had 25 yards. Kelce has actually only surpassed the 60-yard mark twice this season, in weeks one and four. While Kelce is definitely a favorite target of Mahomes, the yards haven’t been there for the All-Pro tight end. I expect Kelce’s yard shortage to continue here against the Bills, who have held opposing tight ends in check all season, allowing only an average of 31.4 receiving yards per game to opposing tight ends. 

Best Bet #3: Clyde Edwards-Helaire OVER 20.5 Receiving Yards (-110)

Edwards-Helaire is still trying to get his season started on the ground this year–he’s only got 223 yards through five games, and he only has one game with 10+ attempts so he’s not exactly the focal point of this Chiefs offense (surprise, surprise). However, CEH has made an impact on the receiving side of things, averaging three catches a game for 27.4 yards. If he had gained one more receiving yard last week, he would’ve surpassed the 20.5 receiving yards mark for the fourth time this season–and seeing as how the Bills allow an average of 30.2 receiving yards to opposing running backs, this one feels like a bit of a lock. 

Best Bet #4: Buffalo Bills -2.5 (-115)

That’s right–I’m putting my foot down and I’m taking the Bills. I think their defense is going to surprise the Chiefs early, and I wouldn’t be shocked if Mahomes threw an interception or two (currently at -115) throughout the course of the game. The Bills still have a bad taste in their mouth from last year’s divisional round loss, and they’ve had a whole lot of time to stew it over and manifest that anger into tough, hard-nosed football. It’ll be a great game, but I think the Bills win fairly comfortably. 

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