Los Angeles Rams vs San Francisco 49ers Picks - Michigan Sports Betting

Last Updated: Nov 12th 2021   Published: Nov 12th 2021   1 Min Read
Los Angeles Rams vs San Francisco 49ers Picks - Michigan Sports Betting
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Author: Nick Noe

Monday Night Football! Sean McVay and the Rams will be looking to make a point against a SF defense that struggles to cover and tackle opponents.

Game: November 15th | 8:15 PM ET | ESPN

BetMGM Betting Line: Rams -4 (-110) @ 49ers

Both teams are coming off disappointing losses last week. The Rams organization is feeling good with recent high profile signings on Defense (Von Miller) and Offense (Odell Beckham Jr.). At the time of this article it is unknown if either of the stars will make their LA Debuts.

The 49ers are sitting at the bottom of the NFC West standings and have a grim outlook on this game due to problems defensively and sloppy play on offense.


The Rams are 4-0 on the road this season but should not overlook their Division rival who has beat them 4 times in a row. The underdog has covered four straight games in this series.

The 49ers are 0-4 at home and are just 1-8 at Levi's Stadium the past two years.

Monday is always a big night for Michigan Sports Betting apps. This game will be of interest to Michiganders as former Detroit Lions Quarterback Matthew Stafford will be in the spotlight. The Rams have the majority of the early action in the betting markets and we like them to win this game

OddsSeeker Prediction - MI Betting Odds

NFL Football Expert Pick: Rams star studded lineup will be too much for 49ers to handle. Take Rams to cover!

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