Week 10 NFL Picks, Popular Bets, & Sleepers

Last Updated: Nov 10th 2021   Published: Nov 10th 2021   3 Min Read
Week 10 NFL Picks, Popular Bets, & Sleepers
Image © George Walker IV / Tennessean.com / USA TODAY NETWORK

The Titans, who have won five straight now, have the longest active winning streak. They've been one of the most popular teams for NFL bets, and that won't change this week when they host a Saints team coming off a disappointing home loss to Atlanta. Caesars Sportsbook lists Tennessee as a three-point favorite in the latest Week 10 live NFL odds.

This week, Patrick Mahomes and the Chiefs are 2.5-point favorites over the Raiders in a divisional matchup. Titans vs. Saints is one of five games with NFL spreads of three points or fewer, as oddsmakers are expecting competitive contests. 



Top Week 10 NFL Predictions

One of the strongest predictions in Week 10 is that the Bills (-13) cover the spread against the Jets. Despite Buffalo's Week 9 defeat. The Bills lead the league in scoring defense and are fourth in scoring offense making them one of the favorites for Superbowl Predictions, while the Jets rank among the bottom six in both. Buffalo is known for having a comeback after losses, as it has outscored its two opponents 61-11 following the team's defeats.

The Jets have not confirmed who their quarterback will be on Sunday with both Zach Wilson (knee) and Mike White (arm) dealing with injuries; Josh Johnson, who was playing in the XFL last year, would be the next best man up for the role. Then to add insult to injury, top receiver Corey Davis has missed the last two games and the Jets offense will definitely have an uphill battle against Buffalo's top-ranked defense. 

We foresee New York turning the ball over three times and failing to crack 300 yards of total offense, facing a Josh Allen who is projected to bounce back and have over 300 total yards by himself. The projections favor Buffalo to win by 20 points, the Bills cover the 13-point spread in well over 60 percent of simulations.

Another projection for this week is the Broncos (-2.5) cover against the Eagles at home. In week 9 Denver thoroughly dominated the Cowboys on the road and their No. 2 scoring defense held the elite Cowboys offense to season-lows in points (16) and yards (290) giving one of the most impressive performances of the season. Even with the trading of Von Miller, the Broncos' defense slowed down Dak Prescott and held him to his lowest passer rating over a full game in nearly two years.

This week that same defense faces a much “younger” quarterback, Jalen Hurts, who has fewer weapons in his arsenal and will have to travel to Denver. The Eagles' rushing attack isn't potent enough to offset the lack of production in the passing game, especially when Hurts has only finished under 200 passing yards in four of his last five games. We do not foresee any Eagles running back topping 35 rushing yards, while Denver's Melvin Gordon and Javonte Williams are each expected to go over 50.

The Broncos have won two straight against the spread, while the Eagles are 3-5 against the number as underdogs. SportsLine's model has the Broncos (-2.5) covering almost 60 percent of the time, while the Under (44.5) hits in well over 50 percent of simulations.

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